Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.68 |
| ▸ | CDK8 | P49336 | 3/20 | 0.67 |
| ▸ | RAF1 | P04049 | 8/20 | 0.67 |
| ▸ | BRAF | P15056 | 2/20 | 0.66 |
| ▸ | FLT1 | P17948 | 2/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.64 |
| ▸ | CA7 | P43166 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | PLK4 | O00444 | 1/20 | 0.61 |
| ▸ | CIT | O14578 | 1/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
| ▸ | MUSK | O15146 | 1/20 | 0.61 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.61 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.61 |
| ▸ | MLNR | O43193 | 1/20 | 0.61 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16621058 | 1.00 | KDR (0.68) | KDRCDK8RAF1BRAFFLT1 | |
| SCHEMBL716399 | 0.92 | KDR (0.80) | KDRCDK8RAF1EPHX2CA7 | |
| SCHEMBL13556629 | 0.90 | RAF1 (0.72) | KDRCDK8RAF1BRAFFLT1 | |
| SCHEMBL6014335 | 0.90 | RAF1 (0.79) | KDRCDK8RAF1FLT1EPHX2 | |
| SCHEMBL6014647 | 0.88 | RAF1 (0.80) | KDRCDK8RAF1BRAFFLT1 | |
| SCHEMBL16628140 | 0.86 | KDR (0.70) | KDRCDK8RAF1BRAFFLT1 | |
| SCHEMBL938819 | 0.86 | KDR (0.70) | KDRCDK8RAF1BRAFFLT1 | |
| SCHEMBL936533 | 0.85 | RAF1 (0.73) | KDRCDK8RAF1BRAFFLT1 | |
| SCHEMBL30462521 | 0.85 | RAF1 (0.73) | KDRCDK8RAF1BRAFFLT1 | |
| SCHEMBL16621046 | 0.84 | KDR (0.67) | KDRCDK8RAF1BRAFFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025083280-A1 | SORAFENIB ANALOGS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITAT DE BARCELONA (ES) | 2025-04-24 | — | — | WO | disclosed |