Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22495415 | 1.00 | MAPT (0.55) | MAPTNPSR1SMN1; SMN2TSHRLMNA | |
| SCHEMBL31504261 | 0.88 | HTR1A (0.57) | MAPTSMN1; SMN2TSHRLMNAUSP2 | |
| SCHEMBL22495213 | 0.88 | HTR1A (0.57) | MAPTSMN1; SMN2TSHRLMNAUSP2 | |
| SCHEMBL22495289 | 0.87 | MAPT (0.58) | MAPTSMN1; SMN2TSHRLMNAUSP2 | |
| SCHEMBL22495397 | 0.84 | KMT2A (0.54) | MAPTSMN1; SMN2TSHRLMNAUSP2 | |
| SCHEMBL31504277 | 0.84 | KMT2A (0.54) | MAPTSMN1; SMN2TSHRLMNAUSP2 | |
| SCHEMBL31504269 | 0.84 | MAPT (0.52) | MAPTNPSR1SMN1; SMN2TSHRLMNA | |
| SCHEMBL22495225 | 0.84 | MAPT (0.52) | MAPTNPSR1SMN1; SMN2TSHRLMNA | |
| SCHEMBL22495286 | 0.84 | PANK3 (0.48) | MAPTNPSR1SMN1; SMN2TSHRLMNA | |
| SCHEMBL31504187 | 0.84 | PANK3 (0.48) | MAPTNPSR1SMN1; SMN2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728234-B1 | RADIOLABELED COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2025-05-14 | — | — | EP | claimed |