Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027269 | 0.87 | CA1 (0.47) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL29661877 | 0.83 | HPRT1 (0.64) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL22288269 | 0.83 | HPRT1 (0.64) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL1344272 | 0.79 | CA1 (0.60) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL1933777 | 0.79 | HPRT1 (0.58) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL2854731 | 0.79 | HPRT1 (0.58) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL30363731 | 0.79 | CA1 (0.60) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL194524 | 0.79 | HPRT1 (0.58) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL5081427 | 0.79 | HPRT1 (0.58) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL17530125 | 0.78 | TRPM4 (0.46) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1538148-B1 | CHIRAL SENSOR | JAPAN SCIENCE & TECH AGENCY (JP) | 2007-01-10 | — | — | EP | claimed |
| CN-112955422-B | polycyclic compound | 三菱瓦斯化学株式会社 | 2023-08-22 | — | — | CN | disclosed |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | MITSUBISHI GAS CHEMICAL CO (JP) | 2021-11-18 | — | — | US | disclosed |
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2021-11-04 | — | — | US | disclosed |
| CN-112955422-A | Polycyclic compounds | 三菱瓦斯化学株式会社 | 2021-06-11 | — | — | CN | disclosed |
| WO-2020079225-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2020-04-23 | — | — | WO | disclosed |
| WO-2020080558-A1 | POLYCYCLIC COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-04-23 | — | — | WO | disclosed |
| US-8722842-B2 | Optical film and image display device | NITTO DENKO CORPORATION (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8218937-B2 | Optical film, image display device, diethynylfluorene, and polymer thereof | NITTO DENKO CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100110554-A1 | OPTICAL FILM AND IMAGE DISPLAY DEVICE | NITTO DENKO CORPORATION (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100003490-A1 | OPTICAL FILM, IMAGE DISPLAY DEVICE, DIETHYNYLFLUORENE, AND POLYMER THEREOF | NITTO DENKO CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
| US-7358403-B2 | Chiral sensor | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-04-15 | — | — | US | disclosed |
| EP-1538148-B1 | CHIRAL SENSOR | JAPAN SCIENCE & TECH AGENCY (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-20050227366-A1 | optically active compound having an unsaturated bond at an optically active binding site, wherein the unsaturated bond and a fluorescent substituent or a substituent capable of imparting fluorescence are united in a conjugated manner; capable of recognizing a chiral compound in a high sensitivity | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-10-13 | — | — | US | disclosed |
| EP-1538148-A1 | CHIRAL SENSOR | Japan Science and Technology Agency (JP) | 2005-06-08 | — | — | EP | disclosed |
| JP-2005097230-A | BISAMINOPHENOL DERIVATIVE | SUMITOMO BAKELITE CO LTD | 2005-04-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | CBR1, C1R, CBR3 | HPRT1 2184/4885ALDH1A1 342/4885HSD17B10 1405/4885 |
| US-20100003490-A1 | OPTICAL FILM, IMAGE DISPLAY DEVICE, DIETHYNYLFLUORENE, AND POLYMER THEREOF | PDCD2L, FMNL1, MACF1 | HPRT1 3819/4885ALDH1A1 2272/4885HSD17B10 147/4885 |
| US-20050227366-A1 | optically active compound having an unsaturated bond at an optically active binding site, wherein the unsaturated bond and a fluorescent substituent or a substituent capable of imparting fluorescence are united in a conjugated manner; capable of recognizing a chiral compound in a high sensitivity | FASN, DBI, SCD | HPRT1 2924/4885ALDH1A1 304/4885HSD17B10 406/4885 |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | CBR1, CBR3, C1R | HPRT1 2418/4885ALDH1A1 409/4885HSD17B10 1119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.