MACF1

Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 · Q9UPN3 · MACF1 on Sugi Atlas →

0 patent compounds predicted against MACF1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MACF1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
LCL161 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis PHASE2COMPLETED
Biologic Correlative Taxotere/AC PHASE2COMPLETED
NCF Gene & TNFSF4 in SLE Patients nanUNKNOWN
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF) nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Linkage Study in Familial Pulmonary Fibrosis nanCOMPLETED
Investigating the Role of Luminal Pressure on Arteriovenous Fistula Maturation nanUNKNOWN
Epithelial Mesenchymal Transition and Periodontitis nanUNKNOWN
Effect Inhaled Nitric Oxide in Adult Liver Transplant nanNOT_YET_RECRUITING
The Role of Muscle Protein Breakdown in the Regulation of Muscle Quality in Frail Elderly Individuals nanCOMPLETED
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease nanCOMPLETED
Genes of Hypertension in African Americans nanCOMPLETED
Genetic Determinants of Exercise-Induced Muscle Damage (POLYGENDOMUS) nanRECRUITING
Role of Macrophage Migratory Inhibitory Factor in Systemic Sclerosis nanUNKNOWN
Diet Intervention and GEnetic STudy (DIGEST-Pilot) nanUNKNOWN
Pulmonary Hypertension--Mechanisms and Family Registry nanCOMPLETED
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients nanCOMPLETED
Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure nanRECRUITING
Autophagy Bladder Cancer nanUNKNOWN
Role of CD11a in Pathogenesis of Primary ITP and Effect of Immunosuppressive Therapy on Its Level nanCOMPLETED
Cerebellar Mutism Syndrome Study nanRECRUITING
Indoxyl Sulfate Induces Leukocyte-endothelial Interactions Through Up-regulation of ICAM-1 in Acute Kidney Injury nanUNKNOWN
Markers and Mechanisms of Macrovascular Disease in IDDM nanCOMPLETED
Genetics of Rheumatoid Arthritis nanCOMPLETED
Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level nanENROLLING_BY_INVITATION
Comparison of Two Methods to Diagnose Coronary Artery Disease nanCOMPLETED
Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma (MAC) nanRECRUITING
Immune Cell Response to Stimuli nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a MACF1 binder may also engage these)

ProteinNameSimilarity
D3ZHV2 1.000 D3ZHV2 →
Q9QXZ0 1.000 Q9QXZ0 →
Q5GN48 1.000 Q5GN48 →
Q9QXS1 0.998 Q9QXS1 →
Q9JI55 0.997 Q9JI55 →
Q03001 0.996 Q03001 →
P11532 0.995 P11532 →
P30427 0.995 P30427 →
UTRN Utrophin 0.994 landscape →
Q91ZU6 0.994 Q91ZU6 →
O97592 0.994 O97592 →
Q6ZWR6 0.992 Q6ZWR6 →
G3V7L1 0.992 G3V7L1 →
A2CG49 0.992 A2CG49 →
P11533 0.991 P11533 →
P10911 0.991 P10911 →
Q9QVP9 0.991 Q9QVP9 →
Q8NF91 0.991 Q8NF91 →
Q86YR7 0.991 Q86YR7 →
PLEC Plectin 0.990 landscape →
Q0KL02 0.990 Q0KL02 →
DSP Desmoplakin 0.990 landscape →
O75962 0.990 O75962 →
Q13972 0.990 Q13972 →
Q9EQW7 0.990 Q9EQW7 →
O60229 0.990 O60229 →
P97924 0.989 P97924 →
Q12756 0.989 Q12756 →
Q9Z1A9 0.989 Q9Z1A9 →
O54874 0.989 O54874 →