SCHEMBL31505597

SCHEMBL31505597

CNC1(CC(=O)OCc2ccccc2)CN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ HTT P42858 1/20 0.43
▸ MAPT P10636 2/20 0.42
▸ STS P08842 1/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ NPC1 O15118 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ GPR119 Q8TDV5 1/20 0.40
▸ MAPK1 P28482 2/20 0.40
▸ NTSR1 P30989 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ ACHE P22303 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17726836 0.85 MEN1 (0.48) MEN1KMT2AHTTMAPTSTS
SCHEMBL17726568 0.83 MEN1 (0.46) MEN1KMT2AHTTMAPTSTS
SCHEMBL34473910 0.80 KMT2A (0.37) MEN1KMT2AHTTL3MBTL1SMN1; SMN2
SCHEMBL28865052 0.80 SYK (0.44) MEN1KMT2ASTSSMN1; SMN2
SCHEMBL25447134 0.79 MEN1 (0.49) MEN1KMT2AHTTSTSGPR119
SCHEMBL26090865 0.79 SYK (0.43) MEN1KMT2AMAPTSTSL3MBTL1
SCHEMBL3492937 0.78 MEN1 (0.51) MEN1KMT2AHTTSTSNPC1
SCHEMBL31505577 0.78 MEN1 (0.41) MEN1KMT2AHTTSTSL3MBTL1
SCHEMBL27147399 0.78 P2RX7 (0.41) MEN1KMT2ASTSL3MBTL1
SCHEMBL30681417 0.76 P2RX7 (0.41) MEN1KMT2AMAPTSTSL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025101944-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A Plexium, Inc. (US) 2025-05-15 — — WO disclosed
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