Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30667836 | 1.00 | NPC1 (0.39) | NPC1ALDH1A1SMN1; SMN2POLBRAB9A | |
| SCHEMBL26684944 | 0.89 | MEN1 (0.35) | ALDH1A1SMN1; SMN2HPGDHSD17B10ALOX15 | |
| SCHEMBL26860680 | 0.89 | MAP3K14 (0.40) | MAP3K14 | |
| SCHEMBL30668026 | 0.84 | MAP3K14 (0.45) | MAP3K14 | |
| SCHEMBL31507534 | 0.84 | MAP3K14 (0.45) | MAP3K14 | |
| SCHEMBL31507575 | 0.82 | ELANE (0.42) | MAP3K14 | |
| SCHEMBL30667972 | 0.82 | ELANE (0.42) | MAP3K14 | |
| SCHEMBL31507461 | 0.81 | MAP3K14 (0.52) | MAP3K14 | |
| SCHEMBL30667739 | 0.81 | MAP3K14 (0.52) | MAP3K14 | |
| SCHEMBL31507496 | 0.80 | MAP3K14 (0.39) | NPC1SMN1; SMN2RAB9AMAP3K14NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546602-A | Pyrrolidone derivatives as inhibitors of nfkb-induced kinase | 詹森药业有限公司 | 2025-02-28 | — | — | CN | disclosed |