Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 13/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30668026 | 1.00 | MAP3K14 (0.45) | MAP3K14ADORA1ELANECA1CA2 | |
| SCHEMBL30667972 | 0.92 | ELANE (0.42) | MAP3K14ELANE | |
| SCHEMBL31507575 | 0.92 | ELANE (0.42) | MAP3K14ELANE | |
| SCHEMBL31507461 | 0.91 | MAP3K14 (0.52) | MAP3K14 | |
| SCHEMBL30667739 | 0.91 | MAP3K14 (0.52) | MAP3K14 | |
| SCHEMBL31507608 | 0.89 | MAP3K14 (0.40) | MAP3K14 | |
| SCHEMBL30667932 | 0.89 | MAP3K14 (0.40) | MAP3K14 | |
| SCHEMBL26684440 | 0.89 | MAP3K14 (0.49) | MAP3K14 | |
| SCHEMBL30668012 | 0.88 | MAP3K14 (0.58) | MAP3K14 | |
| SCHEMBL31507482 | 0.84 | NPC1 (0.39) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546602-A | Pyrrolidone derivatives as inhibitors of nfkb-induced kinase | 詹森药业有限公司 | 2025-02-28 | — | — | CN | disclosed |