SCHEMBL31507627

SCHEMBL31507627

CC(O)(c1ccc(F)cc1)C(F)(F)CCOc1c(F)ccc(-c2ccc3nc(N)nn3c2)c1F

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 3/20 0.33
▸ PIK3CG P48736 3/20 0.33
▸ CYP11B2 P19099 1/20 0.32
▸ PIK3CA P42336 2/20 0.32
▸ PIK3CB P42338 2/20 0.32
▸ CSNK1D P48730 3/20 0.32
▸ CSNK1E P49674 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31507768 0.87 PIK3CG (0.35) PIK3CDPIK3CGPIK3CAPIK3CB
SCHEMBL31507867 0.86 PIK3CD (0.31) PIK3CDPIK3CG
SCHEMBL31507660 0.81 PIK3CG (0.34) PIK3CDPIK3CGPIK3CAPIK3CB
SCHEMBL31507702 0.80 PIK3CG (0.35) PIK3CDPIK3CGPIK3CAPIK3CB
SCHEMBL31507713 0.80 PIK3CG (0.34) PIK3CDPIK3CGPIK3CAPIK3CB
SCHEMBL31507781 0.79 PIK3CG (0.34) PIK3CDPIK3CGPIK3CAPIK3CB
SCHEMBL31507690 0.79 PIK3CG (0.34) PIK3CDPIK3CGPIK3CAPIK3CB
SCHEMBL31507776 0.79 PIK3CG (0.35) PIK3CDPIK3CGPIK3CAPIK3CB
SCHEMBL31507631 0.78 RIPK1 (0.35) PIK3CDPIK3CGPIK3CAPIK3CB
SCHEMBL31507628 0.78 PIK3CG (0.35) PIK3CDPIK3CGPIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072392-A1 TRIAZOLOPYRIDINYL ETHER LINKED COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 — — WO disclosed
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