⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31509780 | 0.90 | PTK2 (0.30) | — | |
| SCHEMBL31509913 | 0.86 | TRPV1 (0.31) | — | |
| SCHEMBL31509752 | 0.86 | — | — | |
| SCHEMBL31509893 | 0.83 | SSTR4 (0.31) | — | |
| SCHEMBL31509769 | 0.79 | TRPV1 (0.31) | — | |
| SCHEMBL31509730 | 0.78 | — | — | |
| SCHEMBL31509850 | 0.78 | TRPV1 (0.32) | — | |
| SCHEMBL31555442 | 0.75 | PPARA (0.33) | — | |
| SCHEMBL31509839 | 0.73 | L3MBTL1 (0.34) | — | |
| SCHEMBL31509777 | 0.73 | NAMPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250127801-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. | 2025-04-24 | — | — | US | disclosed |
| WO-2025080850-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-04-17 | — | — | WO | disclosed |