Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | WDR5 | P61964 | 2/20 | 0.54 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | IDE | P14735 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389152 | 0.79 | KMT2A (0.55) | KMT2ALMNACYP2C9MAPTALDH1A1 | |
| SCHEMBL3077127 | 0.79 | KMT2A (0.52) | KMT2ALMNACYP2C9MAPTALDH1A1 | |
| SCHEMBL3063914 | 0.78 | KMT2A (0.53) | KMT2ALMNACYP2C9MAPTALDH1A1 | |
| SCHEMBL1306777 | 0.78 | RAB9A (0.71) | KMT2ALMNACYP2C9MAPTALDH1A1 | |
| SCHEMBL29538889 | 0.78 | RAB9A (0.71) | KMT2ALMNACYP2C9MAPTALDH1A1 | |
| SCHEMBL3066903 | 0.77 | KMT2A (0.52) | KMT2ALMNACYP2C9MAPTALDH1A1 | |
| SCHEMBL5738051 | 0.77 | RAB9A (0.70) | KMT2ALMNACYP2C9MAPTALDH1A1 | |
| SCHEMBL5738053 | 0.77 | RAB9A (0.70) | KMT2ALMNACYP2C9MAPTALDH1A1 | |
| SCHEMBL8502308 | 0.76 | RAB9A (0.71) | KMT2ALMNACYP2C9MAPTALDH1A1 | |
| SCHEMBL23988369 | 0.74 | CYP2C9 (0.63) | KMT2ALMNACYP2C9MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921075-B1 | A process for the preparation of pyridine-methylsulfinyl compounds | DIPHARMA FRANCIS SRL (IT) | 2010-03-03 | — | — | EP | disclosed |