Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514430 | 0.83 | TSHR (0.45) | USP2TSHRALDH1A1MAPTHPGD | |
| SCHEMBL2746322 | 0.76 | TSHR (0.61) | USP2TSHRALDH1A1MAPTHPGD | |
| SCHEMBL19140899 | 0.73 | MAPK1 (0.51) | USP2ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL19140752 | 0.73 | MAPK1 (0.44) | USP2ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL26088483 | 0.72 | ALDH1A1 (0.34) | USP2ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL5516804 | 0.72 | TSHR (0.48) | USP2TSHRALDH1A1MAPTHPGD | |
| SCHEMBL1400072 | 0.69 | KDM4E (0.49) | TSHRALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL17629599 | 0.69 | EGLN1 (0.70) | TSHRALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL20546213 | 0.68 | KDM4E (0.47) | TSHRALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL8114138 | 0.68 | USP2 (0.94) | USP2TSHRALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025045145-A1 | WRN HELICASE-INHIBITING BIS-HETEROCYCLIC DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 广州科恩泰生物医药科技有限公司 | 2025-03-06 | — | — | WO | disclosed |