Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | CD38 | P28907 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 2/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | GAK | O14976 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514578 | 0.90 | HTR2A (0.48) | HTR2AMAPTMAPK1AHRHTT | |
| SCHEMBL31514573 | 0.90 | HTR2A (0.50) | HTR2AMAPTMAPK1AHRHTT | |
| SCHEMBL31514566 | 0.89 | HTR2A (0.53) | HTR2AFLT1KDREGFRRAF1 | |
| SCHEMBL31514614 | 0.89 | FLT1 (0.50) | FLT1KDREGFRNTRK1RAF1 | |
| SCHEMBL31514609 | 0.88 | HTR2A (0.50) | HTR2AFLT1KDREGFRRAF1 | |
| SCHEMBL31514628 | 0.86 | HTR2A (0.50) | HTR2AFLT1KDREGFRRAF1 | |
| SCHEMBL31514565 | 0.81 | CNR2 (0.54) | HTR2AEGFRAURKB | |
| SCHEMBL31514632 | 0.80 | KDR (0.56) | FLT1KDREGFRRAF1BRAF | |
| SCHEMBL31514585 | 0.78 | CD38 (0.48) | FLT1KDREGFRRAF1BRAF | |
| SCHEMBL31514613 | 0.78 | KDR (0.56) | FLT1KDREGFRRAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912429-A | Quinazoline compound with anti-inflammatory activity or pharmaceutically acceptable salt thereof, pharmaceutical composition and application thereof | 安徽医科大学 | 2025-05-02 | — | — | CN | disclosed |