Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CD38 | P28907 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514565 | 0.93 | CNR2 (0.54) | HTR2ACNR2AURKBEGFRTDO2 | |
| SCHEMBL31514585 | 0.91 | CD38 (0.48) | CNR2AURKBCD38FLT1KDR | |
| SCHEMBL31514625 | 0.90 | TDO2 (0.48) | HTR2ACNR2FLT1KDREGFR | |
| SCHEMBL31514592 | 0.90 | TDO2 (0.48) | HTR2ACNR2EGFRTDO2MAP4K4 | |
| SCHEMBL31514606 | 0.90 | CD38 (0.47) | CNR2AURKBCD38FLT1KDR | |
| SCHEMBL31514623 | 0.89 | CNR2 (0.52) | CNR2AURKBEGFRTDO2RAF1 | |
| SCHEMBL31514589 | 0.89 | CNR2 (0.54) | CNR2AURKBCD38DGAT1EGFR | |
| SCHEMBL31514594 | 0.89 | AURKB (0.49) | AURKBCD38DGAT1FLT1KDR | |
| SCHEMBL31514562 | 0.89 | CNR2 (0.47) | CNR2CD38EGFRMAP4K4ERN1 | |
| SCHEMBL31514558 | 0.88 | HTR2A (0.53) | HTR2AAURKBCD38DGAT1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912429-A | Quinazoline compound with anti-inflammatory activity or pharmaceutically acceptable salt thereof, pharmaceutical composition and application thereof | 安徽医科大学 | 2025-05-02 | — | — | CN | disclosed |