Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.46 |
| ▸ | CD38 | P28907 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514581 | 0.90 | EGFR (0.54) | EGFRAURKBCNR2DGAT1MAP4K4 | |
| SCHEMBL31514595 | 0.89 | MAP4K4 (0.51) | EGFRHTTAURKBCNR2MAP4K4 | |
| SCHEMBL31514575 | 0.89 | CNR2 (0.62) | EGFRAURKBCNR2DGAT1MAP4K4 | |
| SCHEMBL31514590 | 0.88 | KDR (0.55) | EGFRHTTHIF1AAURKBDGAT1 | |
| SCHEMBL31514562 | 0.84 | CNR2 (0.47) | EGFRHIF1ACNR2MAP4K4CDK2 | |
| SCHEMBL31514567 | 0.84 | EGFR (0.49) | EGFRHTTAURKBCNR2DGAT1 | |
| SCHEMBL31514559 | 0.83 | MAP4K4 (0.51) | EGFRHTTHIF1AAURKBCNR2 | |
| SCHEMBL31514626 | 0.83 | CNR2 (0.54) | EGFRHTTAURKBCNR2DGAT1 | |
| SCHEMBL8871984 | 0.83 | EGFR (0.58) | EGFRHTTHIF1AMAPK1 | |
| SCHEMBL31514605 | 0.83 | SRC (0.53) | EGFRHTTAURKBMAP4K4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912429-A | Quinazoline compound with anti-inflammatory activity or pharmaceutically acceptable salt thereof, pharmaceutical composition and application thereof | 安徽医科大学 | 2025-05-02 | — | — | CN | disclosed |