Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514559 | 0.90 | MAP4K4 (0.51) | MAP4K4MAPTMAPK1HTTAHR | |
| SCHEMBL31514626 | 0.90 | CNR2 (0.54) | MAP4K4MAPTMAPK1HTTAHR | |
| SCHEMBL31514605 | 0.89 | SRC (0.53) | MAP4K4MAPTMAPK1HTTAHR | |
| SCHEMBL31514587 | 0.89 | EGFR (0.54) | MAP4K4MAPK1HTTCNR2EGFR | |
| SCHEMBL31514567 | 0.86 | EGFR (0.49) | MAP4K4MAPTMAPK1HTTAHR | |
| SCHEMBL31514581 | 0.84 | EGFR (0.54) | MAP4K4CNR2EGFRCD38AURKB | |
| SCHEMBL31514562 | 0.84 | CNR2 (0.47) | MAP4K4MAPK1CNR2ALDH1A1CYP1A2 | |
| SCHEMBL31514575 | 0.83 | CNR2 (0.62) | MAP4K4CNR2EGFRAURKB | |
| SCHEMBL31514590 | 0.83 | KDR (0.55) | MAP4K4MAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL31514568 | 0.83 | RIPK2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912429-A | Quinazoline compound with anti-inflammatory activity or pharmaceutically acceptable salt thereof, pharmaceutical composition and application thereof | 安徽医科大学 | 2025-05-02 | — | — | CN | disclosed |