Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514937 | 0.90 | COMT (0.49) | COMTTSHRHSP90AA1HSP90AB1HPGD | |
| SCHEMBL31514936 | 0.88 | COMT (0.70) | COMTHSP90AA1HSP90AB1HPGDALDH1A1 | |
| SCHEMBL31514943 | 0.85 | COMT (0.55) | COMTTSHRHSP90AA1HSP90AB1HPGD | |
| SCHEMBL31514932 | 0.85 | COMT (0.55) | COMTTSHRHSP90AA1HSP90AB1HPGD | |
| SCHEMBL31514940 | 0.85 | COMT (0.50) | COMTTSHRHSP90AA1HSP90AB1HPGD | |
| SCHEMBL31514939 | 0.85 | COMT (0.50) | COMTTSHRHSP90AA1HSP90AB1HPGD | |
| SCHEMBL29642891 | 0.84 | COMT (0.79) | COMTHSP90AA1HSP90AB1HPGDCYP1A2 | |
| SCHEMBL18987105 | 0.84 | COMT (0.79) | COMTHSP90AA1HSP90AB1HPGDCYP1A2 | |
| SCHEMBL31514946 | 0.84 | COMT (0.47) | COMTTSHRHSP90AA1HSP90AB1MC4R | |
| SCHEMBL31514934 | 0.84 | COMT (0.47) | COMTTSHRHSP90AA1HSP90AB1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390351-B1 | NOVEL BICYCLIC-COMPOUNDS FOR USE AS A MEDICAMENT, IN PARTICULAR FOR TREATMENT OF PARKINSON'S DISEASE | KOESTER HUBERT (DE) | 2025-02-26 | — | — | EP | claimed |
| EP-3390351-B1 | NOVEL BICYCLIC-COMPOUNDS FOR USE AS A MEDICAMENT, IN PARTICULAR FOR TREATMENT OF PARKINSON'S DISEASE | KOESTER HUBERT (DE) | 2025-02-26 | — | — | EP | disclosed |