Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 17/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.36 |
| ▸ | GSK3B | P49841 | 9/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31516818 | 0.90 | P2RX7 (0.40) | P2RX7CDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL31516924 | 0.89 | P2RX7 (0.44) | P2RX7CDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL31516854 | 0.89 | P2RX7 (0.39) | P2RX7CDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL31517227 | 0.84 | CDK2 (0.44) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL31516946 | 0.84 | CDK2 (0.37) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL31516762 | 0.84 | CDK2 (0.58) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL31516900 | 0.84 | CCNE1 (0.36) | CDK2CCNE1GSK3BNPC1RAB9A | |
| SCHEMBL31587181 | 0.83 | CDK2 (0.38) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL31516982 | 0.82 | KCNQ2 (0.39) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL31517548 | 0.82 | CCNE1 (0.36) | CDK2CCNE1GSK3BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025040546-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-02-27 | — | — | WO | claimed |
| WO-2025040546-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-02-27 | — | — | WO | disclosed |