⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16803677 | 0.82 | GSK3A (0.36) | — | |
| SCHEMBL1593290 | 0.75 | KMT2A (0.47) | — | |
| SCHEMBL8015569 | 0.73 | KMT2A (0.50) | — | |
| Ammonia Solution, Strong SCHEMBL3939167 | 0.73 | KMT2A (0.46) | — | |
| SCHEMBL16803471 | 0.73 | KMT2A (0.50) | — | |
| SCHEMBL16664269 | 0.72 | HRH4 (0.51) | — | |
| SCHEMBL14723206 | 0.70 | MKNK1 (0.33) | — | |
| SCHEMBL25261249 | 0.70 | KMT2A (0.34) | — | |
| SCHEMBL25204734 | 0.70 | KMT2A (0.31) | — | |
| SCHEMBL25261248 | 0.70 | KMT2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025040546-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-02-27 | — | — | WO | disclosed |