Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glutamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.72 |
| ▸ | GRM6 | O15303 | 2/20 | 0.72 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.72 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.72 |
| ▸ | GSR | P00390 | 2/20 | 0.72 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.72 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.72 |
| ▸ | GRM5 | P41594 | 1/20 | 0.72 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.72 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.72 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.72 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.72 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.72 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.72 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.72 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.72 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.72 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamic Acid SCHEMBL8843016 | 0.94 | GRM8 (0.69) | GRM8GRM6GRM7GRM4GSR | |
| Glutamic Acid SCHEMBL8843019 | 0.94 | GRM8 (0.69) | GRM8GRM6GRM7GRM4GSR | |
| D-Glutamate SCHEMBL25353892 | 0.90 | GRM8 (0.75) | GRM8GRM6GRM7GRM4GSR | |
| D-Glutamate SCHEMBL28070259 | 0.90 | GRM8 (0.75) | GRM8GRM6GRM7GRM4GSR | |
| Glutamic Acid SCHEMBL9681578 | 0.90 | GRM8 (0.75) | GRM8GRM6GRM7GRM4GSR | |
| D-Glutamate SCHEMBL28283103 | 0.90 | GRM8 (0.75) | GRM8GRM6GRM7GRM4GSR | |
| D-Glutamate SCHEMBL28742738 | 0.90 | GRM8 (0.82) | GRM8GRM6GRM7GRM4GSR | |
| Glutamic Acid SCHEMBL1667361 | 0.90 | GRM8 (0.82) | GRM8GRM6GRM7GRM4GSR | |
| D-Glutamate SCHEMBL1667360 | 0.90 | GRM8 (0.82) | GRM8GRM6GRM7GRM4GSR | |
| Glutamic Acid SCHEMBL5692202 | 0.88 | GRM8 (0.78) | GRM8GRM6GRM7GRM4GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894823-A | Stable silicic acid solutions | 巴尔拉有限公司 | 2025-04-25 | — | — | CN | disclosed |