Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Glutamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.82 |
| ▸ | GRM6 | O15303 | 2/20 | 0.82 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.82 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.82 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.82 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.82 |
| ▸ | GSR | P00390 | 1/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.82 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.82 |
| ▸ | GRM5 | P41594 | 1/20 | 0.82 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.82 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.82 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.82 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.82 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.82 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.82 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.82 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.82 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.82 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL28742738 | 1.00 | GRM8 (0.82) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL1667360 | 1.00 | GRM8 (0.82) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL5692199 | 0.98 | GRM8 (0.78) | GRM8GRM6GRM7GRM4GRIN2D | |
| Glutamic Acid SCHEMBL28070258 | 0.98 | GRM8 (0.78) | GRM8GRM6GRM7GRM4GRIN2D | |
| Glutamic Acid SCHEMBL5692202 | 0.98 | GRM8 (0.78) | GRM8GRM6GRM7GRM4GRIN2D | |
| Glutamic Acid SCHEMBL29259695 | 0.98 | GRM8 (0.78) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL29259696 | 0.98 | GRM8 (0.78) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL5691701 | 0.98 | GRM8 (0.78) | GRM8GRM6GRM7GRM4GRIN2D | |
| Glutamic Acid SCHEMBL27887685 | 0.96 | GRM8 (0.75) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL29211069 | 0.91 | GRM8 (0.75) | GRM8GRM6GRM7GRM4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103880663-A | Aspirin preparation method | QINGDAO KDN BIOTECH CO LTD | 2014-06-25 | — | — | CN | claimed |
| CN-102180792-B | Method for preparing aspirin | UNIV SHENYANG CHEMICAL TECH | 2013-06-19 | — | — | CN | claimed |
| CN-102039179-B | Catalytic composition for preparing amide and method for preparing amide | CHINA PETROCHEMICAL DEV CORP | 2013-03-06 | — | — | CN | claimed |
| CN-102180792-A | Method for preparing aspirin | UNIV SHENYANG CHEMICAL TECH | 2011-09-14 | — | — | CN | claimed |
| CN-102039179-A | Catalytic composition for preparing amide and method for preparing amide | CHINA PETROCHEMICAL DEV CORP | 2011-05-04 | — | — | CN | claimed |
| US-20260034169-A1 | STABILISED SILICIC ACID SOLUTIONS | BARLAA B.V. (NL) | 2026-02-05 | — | — | US | disclosed |
| EP-4565530-A1 | STABILISED SILICIC ACID SOLUTIONS | Barlaa B.V. (NL) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024028039-A1 | STABILISED SILICIC ACID SOLUTIONS | BARLAA B.V. (NL) | 2024-02-08 | — | — | WO | disclosed |
| CN-103880663-A | Aspirin preparation method | QINGDAO KDN BIOTECH CO LTD | 2014-06-25 | — | — | CN | disclosed |
| CN-102180792-B | Method for preparing aspirin | UNIV SHENYANG CHEMICAL TECH | 2013-06-19 | — | — | CN | disclosed |
| CN-102039179-B | Catalytic composition for preparing amide and method for preparing amide | CHINA PETROCHEMICAL DEV CORP | 2013-03-06 | — | — | CN | disclosed |
| CN-102180792-A | Method for preparing aspirin | UNIV SHENYANG CHEMICAL TECH | 2011-09-14 | — | — | CN | disclosed |
| EP-1529775-A1 | Method for preparation of metal organic acid chelates | JH Biotech, Inc. (US) | 2005-05-11 | — | — | EP | disclosed |
| CN-1150994-C | L-sulforamidate type chiral ionic liquid and its prepn | 华东师范大学 | 2004-05-26 | — | — | CN | disclosed |
| EP-1414952-A2 | PROCESS FOR THE FERMENTATIVE PREPARATION OF L-AMINO ACIDS USING CORYNEFORM BACTERIA | Degussa AG (DE) | 2004-05-06 | — | — | EP | disclosed |
| US-20030092139-A1 | Process for the fermentative preparation of L-amino acids using coryneform bacteria | DEGUSSA AG (DE) | 2003-05-15 | — | — | US | disclosed |
| WO-2003014370-A2 | PROCESS FOR THE FERMENTATIVE PREPARATION OF L-AMINO ACIDS USING CORYNEFORM BACTERIA | DEGUSSA AG (DE) | 2003-02-20 | — | — | WO | disclosed |
| CN-1383920-A | L-sulforamidate type chiral ionic liquid and its prepn | UNIV HUADONG (CN) | 2002-12-11 | — | — | CN | disclosed |
| US-5401770-A | Skin disorders and treatment with zinc amino acid complex | SHISEIDO COMPANY LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-4427762-A | DEVELOPMENT WITH ALKALINE DEVELOPER MIXTURE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034169-A1 | STABILISED SILICIC ACID SOLUTIONS | HAO2, SMS, SSTR2 | GRM8 2290/4885GRM6 2023/4885GRM7 2690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.