Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | HTT | P42858 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | RHOA | P61586 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27915383 | 0.84 | KMT2A (0.59) | MEN1KMT2AHTTALDH1A1HPGD | |
| SCHEMBL6943603 | 0.84 | MEN1 (0.58) | MEN1KMT2AHTTALDH1A1HPGD | |
| SCHEMBL5190460 | 0.84 | KMT2A (0.58) | MEN1KMT2AHTTALDH1A1HPGD | |
| SCHEMBL6629591 | 0.84 | MEN1 (0.58) | MEN1KMT2AHTTALDH1A1HPGD | |
| SCHEMBL5758426 | 0.82 | KMT2A (0.57) | MEN1KMT2AHTTALDH1A1HPGD | |
| SCHEMBL9042374 | 0.81 | MEN1 (0.57) | MEN1KMT2AHTTALDH1A1HPGD | |
| SCHEMBL15140305 | 0.80 | MEN1 (0.54) | MEN1KMT2AHTTALDH1A1HPGD | |
| SCHEMBL27630670 | 0.80 | ALDH1A1 (0.62) | MEN1KMT2AHTTALDH1A1HPGD | |
| SCHEMBL13134244 | 0.80 | MEN1 (0.54) | MEN1KMT2AHTTALDH1A1HPGD | |
| SCHEMBL5190453 | 0.79 | MEN1 (1.00) | MEN1KMT2AHTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931316-B1 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS FOR ACID LABILE DRUGS | SOLVAY PHARM GMBH (DE) | 2010-02-17 | — | — | EP | claimed |
| EP-0992511-B1 | Methods and compositions for determining the sequence of nucleic acid molecules | OPERON BIOTECHNOLOGIES INC (US) | 2009-03-11 | — | — | EP | claimed |
| EP-0868535-B9 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | QIAGEN GENOMICS INC (US) | 2007-05-09 | — | — | EP | claimed |
| EP-0868535-B2 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | QIAGEN GENOMICS INC (US) | 2006-01-04 | — | — | EP | claimed |
| EP-0934276-B1 | ANTHRANILIC ACID DERIVATIVES AS MULTI DRUG RESISTANCE MODULATORS | XENOVA LTD (GB) | 2003-12-17 | — | — | EP | claimed |
| EP-1028164-B1 | Microbial conversion of 2-methylquinoxaline | PFIZER PROD INC (US) | 2003-11-12 | — | — | EP | claimed |
| EP-0691970-A1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | claimed |
| WO-1994022865-A1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | claimed |
| EP-0944582-B1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2003-07-02 | — | — | EP | disclosed |
| EP-0944582-A1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025883-A1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-18 | — | — | WO | disclosed |
| EP-0691970-A1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| EP-0513543-B1 | Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and anticoagulant compositions comprising them. | BEHRINGWERKE AG (DE) | 1995-10-25 | — | — | EP | disclosed |
| WO-1994022865-A1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |
| EP-0513543-A1 | Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and anticoagulant compositions comprising them. | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-11-19 | — | — | EP | disclosed |
| EP-0292729-B1 | PROCESS FOR SOLID PHASE PEPTIDE SYNTHESIS | BACHEM AG (CH) | 1992-04-22 | — | — | EP | disclosed |
| EP-0292729-A2 | Process for solid phase peptide synthesis | BACHEM AG (CH) | 1988-11-30 | — | — | EP | disclosed |