SCHEMBL31521241

SCHEMBL31521241

N[C@@H](c1ccccc1Cl)C1CC1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 5/20 0.41
IDO1 P14902 2/20 0.40
TDO2 P48775 2/20 0.40
IDO2 Q6ZQW0 2/20 0.40
OPRM1 P35372 4/20 0.40
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
NFKB1 P19838 1/20 0.39
PNMT P11086 1/20 0.39
PDCD1LG2 Q9BQ51 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
GLA P06280 1/20 0.38
DPP4 P27487 1/20 0.38
AOC3 Q16853 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31521400 1.00 OPRL1 (0.41) OPRL1IDO1TDO2IDO2OPRM1
SCHEMBL14862296 1.00 OPRL1 (0.41) OPRL1IDO1TDO2IDO2OPRM1
SCHEMBL2676786 1.00 OPRL1 (0.41) OPRL1IDO1TDO2IDO2OPRM1
SCHEMBL14862496 0.92 OPRL1 (0.39) OPRL1IDO1TDO2IDO2OPRM1
SCHEMBL5482781 0.75 MEN1 (0.42) IDO1TDO2CYP3A4ALDH1A1DPP4
SCHEMBL31521476 0.75 OPRL1 (0.45) OPRL1IDO1TDO2OPRM1CYP1A2
SCHEMBL2676471 0.75 MEN1 (0.42) IDO1TDO2CYP3A4ALDH1A1DPP4
SCHEMBL6692753 0.75 ESR1 (0.43) OPRL1IDO1OPRM1CYP3A4PDCD1LG2
SCHEMBL2504578 0.75 OPRL1 (0.45) OPRL1IDO1TDO2OPRM1CYP1A2
SCHEMBL22338552 0.73 OPRL1 (0.40) OPRL1OPRM1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096957-A1 RAS-PI3K INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed