Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22338551 | 0.92 | TAS1R3 (0.42) | OPRL1AOC3ADRB2ADRB1CYP1A2 | |
| SCHEMBL22303858 | 0.77 | ADRB2 (0.40) | OPRL1AOC3ADRB2ADRB1CYP2D6 | |
| SCHEMBL12473635 | 0.74 | ADRB2 (0.42) | OPRL1ADRB2ADRB1CYP1A2CYP3A4 | |
| SCHEMBL31521241 | 0.73 | OPRL1 (0.41) | OPRL1AOC3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14862296 | 0.73 | OPRL1 (0.41) | OPRL1AOC3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31521476 | 0.73 | OPRL1 (0.45) | OPRL1AOC3ADRB2ADRB1CYP1A2 | |
| SCHEMBL2504578 | 0.73 | OPRL1 (0.45) | OPRL1AOC3ADRB2ADRB1CYP1A2 | |
| SCHEMBL2676786 | 0.73 | OPRL1 (0.41) | OPRL1AOC3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31521400 | 0.73 | OPRL1 (0.41) | OPRL1AOC3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24725717 | 0.72 | ADRB2 (0.46) | AOC3ADRB2ADRB1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| US-10934283-B2 | COMT inhibiting methods and compositions | LIEBER INSTITUTE, INC. (US) | 2021-03-02 | — | — | US | disclosed |
| WO-2020163554-A1 | IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2020-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10934283-B2 | COMT inhibiting methods and compositions | COMT, MAOB, MAOA | OPRL1 66/4885AOC3 380/4885ADRB2 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.