SCHEMBL31521682

SCHEMBL31521682

O=c1cc(N2CCC3(CCNC3)CC2)c2ccccc2[nH]1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.54
KDR P35968 1/20 0.48
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
USP2 O75604 4/20 0.41
CYP2D6 P10635 4/20 0.41
DRD2 P14416 1/20 0.41
CYP1A2 P05177 3/20 0.41
CYP2C19 P33261 2/20 0.41
TNKS2 Q9H2K2 1/20 0.41
ALDH1A1 P00352 5/20 0.40
EGFR P00533 1/20 0.40
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
CYP3A4 P08684 3/20 0.39
MAPK1 P28482 3/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31521643 0.93 CYP11B1 (0.46) CYP11B1KDRSLC6A2SLC6A4SLC6A3
SCHEMBL31521668 0.93 ALDH1A1 (0.49) CYP11B1KDRSLC6A2SLC6A4SLC6A3
SCHEMBL31521642 0.92 KDR (0.53) CYP11B1KDRSLC6A2SLC6A4SLC6A3
SCHEMBL31521673 0.88 KDR (0.43) CYP11B1KDRUSP2CYP2D6CYP1A2
SCHEMBL31521650 0.83 TSHR (0.49) KDRUSP2CYP2D6CYP1A2CYP2C19
SCHEMBL31521684 0.82 KDR (0.68) KDRCYP2D6CYP1A2CYP2C19TNKS2
SCHEMBL5124241 0.82 KDR (0.68) KDRCYP2D6CYP1A2CYP2C19TNKS2
SCHEMBL31521644 0.81 ALDH1A1 (0.47) KDRSLC6A2SLC6A4SLC6A3USP2
Hydrochloric Acid SCHEMBL9128302 0.81 KDR (0.66) KDRCYP2D6CYP1A2CYP2C19TNKS2
SCHEMBL29018544 0.78 ALDH1A1 (0.51) KDRCYP1A2CYP2C19TNKS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025095271-A1 NOVEL QUINOLINE-2(1H)-ONE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF 한국과학기술연구원 2025-05-08 WO disclosed