SCHEMBL31522591

SCHEMBL31522591

CC(C)(NC(=O)OC1CN2CCC1CC2)c1ccc(F)c(Br)c1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ NTMT1 Q9BV86 17/20 0.55
▸ UGCG Q16739 1/20 0.52
▸ CHRNA7 P36544 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12614723 0.85 CHRNA7 (0.66) NTMT1UGCGCHRNA7
SCHEMBL29357375 0.85 CHRNA7 (0.66) NTMT1UGCGCHRNA7
SCHEMBL12614720 0.85 CHRNA7 (0.66) NTMT1UGCGCHRNA7
SCHEMBL31522582 0.84 NTMT1 (0.61) NTMT1UGCG
SCHEMBL31522589 0.84 NTMT1 (0.58) NTMT1UGCGCHRNA7
SCHEMBL31522585 0.83 NTMT1 (0.57) NTMT1UGCGCHRNA7
SCHEMBL31591720 0.83 NTMT1 (0.51) NTMT1UGCG
SCHEMBL29360341 0.83 NTMT1 (0.56) NTMT1CHRNA7
SCHEMBL31522593 0.82 NTMT1 (0.57) NTMT1UGCG
SCHEMBL12614555 0.82 NTMT1 (0.58) NTMT1UGCGCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4559918-A2 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS Genzyme Corporation (US) 2025-05-28 — — EP disclosed
EP-3673906-B1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GENZYME CORP (US) 2025-05-14 — — EP disclosed
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