Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 19/20 | 0.68 |
| ▸ | THRB | P10828 | 19/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.59 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28865171 | 0.85 | THRA (0.66) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL29986365 | 0.83 | THRA (0.59) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL2924045 | 0.81 | THRA (1.00) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL29987066 | 0.80 | THRA (0.62) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL29987337 | 0.79 | THRA (0.58) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL22743670 | 0.77 | THRA (0.77) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL29986850 | 0.77 | THRA (0.55) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL24032592 | 0.76 | THRA (0.81) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL23441631 | 0.75 | THRA (0.80) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL16919814 | 0.75 | THRA (0.68) | THRATHRBCYP2C9UGT1A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454069-B | 1,2, 4-Triazine-3, 5-dione compound, and preparation method and application thereof | 昆药集团股份有限公司 | 2025-03-14 | — | — | CN | disclosed |