SCHEMBL31526191

SCHEMBL31526191

Cc1noc(-c2ccc3c(c2)OCO3)c1CSC[C@H]1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PRMT5 O14744 14/20 0.41
▸ WDR77 Q9BQA1 9/20 0.41
▸ DNMT1 P26358 1/20 0.35
▸ DNMT3B Q9UBC3 1/20 0.35
▸ ADK P55263 1/20 0.34
▸ METTL3 Q86U44 5/20 0.33
▸ RIPK2 O43353 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31526280 0.90 DNMT1 (0.37) PRMT5WDR77DNMT1DNMT3BADK
SCHEMBL31526310 0.90 PRMT5 (0.42) PRMT5WDR77DNMT1DNMT3BADK
SCHEMBL31526301 0.89 DNMT1 (0.38) PRMT5WDR77DNMT1DNMT3BADK
SCHEMBL31526285 0.88 ADK (0.37) PRMT5ADKRIPK2
SCHEMBL31526407 0.88 DNMT1 (0.40) PRMT5WDR77DNMT1DNMT3BADK
SCHEMBL31526288 0.87 DNMT1 (0.37) PRMT5WDR77DNMT1DNMT3BADK
SCHEMBL31526120 0.86 DNMT1 (0.49) PRMT5WDR77DNMT1DNMT3BADK
SCHEMBL31526122 0.85 DNMT1 (0.37) PRMT5WDR77DNMT1DNMT3BADK
SCHEMBL31526142 0.84 RIPK2 (0.39) ADKRIPK2
SCHEMBL31526309 0.83 DNMT1 (0.37) PRMT5WDR77DNMT1DNMT3BADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025098545-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2025-05-15 — — WO disclosed
EP-4553080-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2025-05-14 — — EP disclosed
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