SCHEMBL31526200

Cc1noc(-c2ccccc2)c1CSC[C@H]1O[C@@H](n2cc(-c3ccc([N+](=O)[O-])cc3)c3c(N)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	ADK	P55263	4/20	0.38

▸	SRC	P12931	16/20	0.35

▸	EGFR	P00533	3/20	0.34

▸	ABL1	P00519	2/20	0.33

▸	ABL2	P42684	2/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31526167	0.93	LCK (0.33)	ADK
SCHEMBL31526102	0.91	ADK (0.38)	ADK
SCHEMBL31526141	0.90	ADK (0.39)	ADKSRCEGFRABL1ABL2
SCHEMBL31526240	0.89	ADK (0.39)	ADKSRCEGFRABL1ABL2
SCHEMBL31526444	0.88	ADK (0.39)	ADKSRCEGFRABL1ABL2
SCHEMBL31526195	0.88	ADK (0.39)	ADKSRCEGFRABL1ABL2
SCHEMBL31526123	0.87	ADK (0.37)	ADKSRCEGFRABL1ABL2
SCHEMBL31526293	0.87	ADK (0.50)	ADK
SCHEMBL31526122	0.86	DNMT1 (0.37)	ADK
SCHEMBL31526181	0.86	ADK (0.41)	ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025098545-A1	NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES	USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ)	2025-05-15	—	—	WO	disclosed