SCHEMBL31526225

SCHEMBL31526225

Cc1noc(Cc2ccccc2)c1CSC[C@H]1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DNMT1 P26358 1/20 0.39
▸ DNMT3B Q9UBC3 1/20 0.39
▸ PRMT5 O14744 12/20 0.37
▸ WDR77 Q9BQA1 8/20 0.37
▸ ADK P55263 1/20 0.37
▸ SLC29A1 Q99808 1/20 0.35
▸ METTL3 Q86U44 4/20 0.35
▸ GNMT Q14749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31526407 0.89 DNMT1 (0.40) DNMT1DNMT3BPRMT5WDR77ADK
SCHEMBL31526377 0.85 DNMT1 (0.55) DNMT1DNMT3BPRMT5WDR77ADK
SCHEMBL31526132 0.84 DNMT1 (0.39) DNMT1DNMT3BPRMT5WDR77ADK
SCHEMBL31526155 0.84 DNMT1 (0.40) DNMT1DNMT3BPRMT5WDR77ADK
SCHEMBL31526301 0.84 DNMT1 (0.38) DNMT1DNMT3BPRMT5WDR77ADK
SCHEMBL31526258 0.84 PRMT5 (0.36) DNMT1DNMT3BPRMT5WDR77ADK
SCHEMBL31526259 0.84 DNMT1 (0.41) DNMT1DNMT3BPRMT5WDR77ADK
SCHEMBL31526366 0.83 DNMT1 (0.37) DNMT1DNMT3BPRMT5WDR77ADK
SCHEMBL31526194 0.83 DNMT1 (0.40) DNMT1DNMT3BPRMT5WDR77ADK
SCHEMBL31526257 0.83 DNMT1 (0.41) DNMT1DNMT3BPRMT5WDR77ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025098545-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2025-05-15 — — WO disclosed
EP-4553080-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2025-05-14 — — EP disclosed
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