SCHEMBL31526366

Cc1noc(C2CCCCC2)c1CSC[C@H]1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	DNMT1	P26358	1/20	0.37

▸	DNMT3B	Q9UBC3	1/20	0.37

▸	ADK	P55263	1/20	0.37

▸	METTL3	Q86U44	5/20	0.36

▸	PRMT5	O14744	15/20	0.36

▸	WDR77	Q9BQA1	9/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31526241	0.86	DNMT1 (0.38)	DNMT1DNMT3BADKMETTL3PRMT5
SCHEMBL31526339	0.85	DNMT1 (0.53)	DNMT1DNMT3BADKMETTL3PRMT5
SCHEMBL31526301	0.84	DNMT1 (0.38)	DNMT1DNMT3BADKMETTL3PRMT5
SCHEMBL31526407	0.84	DNMT1 (0.40)	DNMT1DNMT3BADKMETTL3PRMT5
SCHEMBL31526309	0.83	DNMT1 (0.37)	DNMT1DNMT3BADKMETTL3PRMT5
SCHEMBL31526225	0.83	DNMT1 (0.39)	DNMT1DNMT3BADKMETTL3PRMT5
SCHEMBL31526288	0.82	DNMT1 (0.37)	DNMT1DNMT3BADKMETTL3PRMT5
SCHEMBL31526280	0.82	DNMT1 (0.37)	DNMT1DNMT3BADKMETTL3PRMT5
SCHEMBL31526155	0.81	DNMT1 (0.40)	DNMT1DNMT3BADKMETTL3PRMT5
SCHEMBL31526258	0.81	PRMT5 (0.36)	DNMT1DNMT3BADKMETTL3PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025098545-A1	NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES	USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ)	2025-05-15	—	—	WO	disclosed