SCHEMBL31526289

SCHEMBL31526289

Cc1noc(-c2ccccc2)c1CSC[C@H]1O[C@@H](n2cc(-c3ccc(-c4cccnc4)cc3)c3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 12/20 0.51
▸ PRMT5 O14744 4/20 0.47
▸ METTL3 Q86U44 3/20 0.47
▸ PRMT9 Q6P2P2 1/20 0.43
▸ DOT1L Q8TEK3 3/20 0.43
▸ SLC28A2 O43868 1/20 0.42
▸ PRMT3 O60678 1/20 0.41
▸ DNMT1 P26358 1/20 0.41
▸ NNMT P40261 1/20 0.41
▸ WDR77 Q9BQA1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31526186 0.93 ADK (0.58) ADKPRMT5PRMT9DOT1LPRMT3
SCHEMBL31526342 0.92 ADK (0.55) ADKPRMT5PRMT9DOT1LPRMT3
SCHEMBL31526135 0.90 ADK (0.51) ADKPRMT5METTL3PRMT9DOT1L
SCHEMBL31526373 0.88 ADK (0.51) ADKPRMT5METTL3PRMT9DOT1L
SCHEMBL31526119 0.88 ADK (0.51) ADKPRMT5DOT1LPRMT3DNMT1
SCHEMBL31526236 0.88 ADK (0.52) ADKPRMT5METTL3DOT1LPRMT3
SCHEMBL31526293 0.87 ADK (0.50) ADKPRMT5METTL3DOT1LPRMT3
SCHEMBL31526307 0.87 ADK (0.48) ADKPRMT5METTL3PRMT9DOT1L
SCHEMBL31526121 0.87 ADK (0.49) ADKPRMT5METTL3PRMT9DOT1L
SCHEMBL31526161 0.86 ADK (0.48) ADKPRMT5METTL3PRMT9DOT1L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025098545-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2025-05-15 — — WO disclosed
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