SCHEMBL31526306

CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CS)O[C@H]1n1cc(-c2ccc(C#N)cc2)c2c(N)ncnc21

nearest known ligand 0.46

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	LCK	P06239	1/20	0.46

▸	KDR	P35968	1/20	0.46

▸	TEK	Q02763	1/20	0.46

▸	ADK	P55263	11/20	0.45

▸	MEN1	O00255	1/20	0.42

▸	RIPK2	O43353	3/20	0.41

▸	DOT1L	Q8TEK3	1/20	0.40

▸	SRC	P12931	3/20	0.40

▸	ABL1	P00519	1/20	0.40

▸	EGFR	P00533	1/20	0.40

▸	ABL2	P42684	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31526127	0.94	ADK (0.50)	LCKKDRTEKADKMEN1
SCHEMBL31526162	0.88	ADK (0.42)	LCKKDRTEKADKMEN1
SCHEMBL31526322	0.82	ADK (0.40)	LCKKDRTEKADKMEN1
SCHEMBL31526247	0.82	ADK (0.40)	LCKKDRTEKADKMEN1
SCHEMBL31526240	0.81	ADK (0.39)	LCKKDRTEKADKMEN1
SCHEMBL31526104	0.81	ADK (0.39)	LCKKDRTEKADKMEN1
SCHEMBL31570708	0.80	ADK (0.56)	ADK
SCHEMBL31526094	0.80	ADK (0.56)	ADK
SCHEMBL31570692	0.75	ADK (0.57)	ADKDOT1L
SCHEMBL31526197	0.74	ADK (0.53)	ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025098545-A1	NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES	USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ)	2025-05-15	—	—	WO	disclosed
EP-4553080-A1	NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES	Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ)	2025-05-14	—	—	EP	disclosed