SCHEMBL31526320

Cc1nsc(-c2ccccc2)c1CSC[C@H]1O[C@@H](n2cc(I)c3c(N)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	ADK	P55263	15/20	0.41

▸	HASPIN	Q8TF76	1/20	0.35

▸	PRMT5	O14744	2/20	0.34

▸	PRMT9	Q6P2P2	1/20	0.34

▸	DOT1L	Q8TEK3	2/20	0.32

▸	PRMT3	O60678	1/20	0.32

▸	DNMT1	P26358	1/20	0.32

▸	NNMT	P40261	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31526305	0.88	ADK (0.41)	ADKHASPINPRMT5PRMT9
SCHEMBL31526104	0.87	ADK (0.39)	ADKPRMT5DOT1LPRMT3DNMT1
SCHEMBL31526181	0.87	ADK (0.41)	ADKHASPINPRMT5PRMT9DOT1L
SCHEMBL31526262	0.87	DNMT1 (0.39)	ADKPRMT5DNMT1
SCHEMBL31526299	0.85	ADK (0.58)	ADKHASPINPRMT5PRMT9DOT1L
SCHEMBL31526192	0.82	ADK (0.41)	ADKHASPINPRMT5PRMT9
SCHEMBL31526179	0.81	ADK (0.41)	ADKHASPINPRMT5PRMT9DOT1L
SCHEMBL31526125	0.80	ADK (0.39)	ADKHASPINPRMT5PRMT9
SCHEMBL31570708	0.77	ADK (0.56)	ADKHASPIN
SCHEMBL31526094	0.77	ADK (0.56)	ADKHASPIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025098545-A1	NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES	USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ)	2025-05-15	—	—	WO	disclosed
EP-4553080-A1	NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES	Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ)	2025-05-14	—	—	EP	disclosed