Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31528231 | 0.82 | TSHR (0.39) | LMNAMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL30778157 | 0.79 | LMNA (0.41) | LMNAMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL25250333 | 0.76 | SMN1; SMN2 (0.40) | LMNAMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL25218808 | 0.76 | LMNA (0.42) | LMNAMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL25250318 | 0.76 | LMNA (0.39) | LMNAMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL19354353 | 0.75 | PDE1B (0.44) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21199702 | 0.75 | LMNA (0.38) | LMNAMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL25206909 | 0.75 | LMNA (0.41) | LMNAMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL29921950 | 0.74 | CCNB2 (0.50) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL27164615 | 0.74 | LMNA (0.37) | LMNAMAPTALDH1A1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423708-B | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-113454086-B | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2025-03-14 | — | — | CN | disclosed |