Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529110 | 0.98 | PAX8 (0.55) | PAX8HDAC1HDAC2BTKTK2 | |
| SCHEMBL31529156 | 0.91 | PAX8 (0.56) | PAX8BTKSMN1; SMN2BRD4CYP3A4 | |
| SCHEMBL31529264 | 0.87 | PAX8 (0.48) | PAX8BTKSMN1; SMN2DOT1L | |
| SCHEMBL31529188 | 0.87 | PAX8 (0.48) | PAX8BTKSMN1; SMN2DOT1L | |
| SCHEMBL31529161 | 0.86 | PAX8 (0.48) | PAX8 | |
| SCHEMBL31529101 | 0.86 | PAX8 (0.48) | PAX8 | |
| SCHEMBL31529259 | 0.84 | PAX8 (0.45) | PAX8BTKSMN1; SMN2BRD4CYP3A4 | |
| SCHEMBL31529304 | 0.84 | PAX8 (0.57) | PAX8HDAC1HDAC2SMN1; SMN2BRD4 | |
| SCHEMBL31529192 | 0.84 | PAX8 (0.55) | PAX8HDAC1HDAC2BTKSMN1; SMN2 | |
| SCHEMBL31529249 | 0.84 | PAX8 (0.59) | PAX8HDAC1HDAC2AURKASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |