Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529121 | 0.86 | PAX8 (0.48) | PAX8SMN1; SMN2BTKTP53HSD17B10 | |
| SCHEMBL31529066 | 0.85 | PAX8 (0.47) | PAX8SMN1; SMN2BTKTP53HSD17B10 | |
| SCHEMBL31529296 | 0.85 | PAX8 (0.47) | PAX8SMN1; SMN2BTKTP53HSD17B10 | |
| SCHEMBL31529275 | 0.85 | PAX8 (0.46) | PAX8SMN1; SMN2BTKTP53HSD17B10 | |
| SCHEMBL31529140 | 0.85 | PAX8 (0.46) | PAX8SMN1; SMN2BTKTP53HSD17B10 | |
| SCHEMBL31529084 | 0.85 | PAX8 (0.46) | PAX8SMN1; SMN2BTKTP53HSD17B10 | |
| SCHEMBL31529300 | 0.82 | PAX8 (0.52) | PAX8SMN1; SMN2BTKTP53HSD17B10 | |
| SCHEMBL31529106 | 0.82 | PAX8 (0.52) | PAX8SMN1; SMN2BTKTP53HSD17B10 | |
| SCHEMBL31529259 | 0.82 | PAX8 (0.45) | PAX8SMN1; SMN2BTKTP53HSD17B10 | |
| SCHEMBL31529156 | 0.82 | PAX8 (0.56) | PAX8SMN1; SMN2BTKTP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |