Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529146 | 0.80 | PAX8 (0.42) | PAX8MKNK2 | |
| SCHEMBL31529131 | 0.79 | PAX8 (0.38) | PAX8 | |
| SCHEMBL31529129 | 0.79 | PAX8 (0.41) | PAX8 | |
| SCHEMBL31529228 | 0.79 | PAX8 (0.39) | PAX8BUB1 | |
| SCHEMBL31529295 | 0.79 | PAX8 (0.44) | PAX8BUB1 | |
| SCHEMBL31529204 | 0.79 | PAX8 (0.44) | PAX8 | |
| SCHEMBL31529080 | 0.79 | PAX8 (0.34) | PAX8BUB1 | |
| SCHEMBL31529155 | 0.71 | ADORA1 (0.43) | — | |
| SCHEMBL31529121 | 0.68 | PAX8 (0.48) | PAX8 | |
| SCHEMBL31529251 | 0.64 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |