⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634001 | 1.00 | — | — | |
| SCHEMBL8348252 | 1.00 | — | — | |
| SCHEMBL13451146 | 1.00 | — | — | |
| SCHEMBL8344751 | 0.94 | — | — | |
| SCHEMBL3156646 | 0.94 | — | — | |
| SCHEMBL13451210 | 0.94 | — | — | |
| SCHEMBL13450788 | 0.94 | — | — | |
| SCHEMBL9655502 | 0.92 | KMT2A (0.36) | — | |
| SCHEMBL7014493 | 0.92 | KMT2A (0.36) | — | |
| SCHEMBL8344822 | 0.92 | KMT2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379494-B1 | FUSED BICYCLIC OR TRICYCLIC AMINO ACIDS | WARNER LAMBERT CO (US) | 2010-03-10 | — | — | EP | disclosed |
| EP-1379494-B1 | FUSED BICYCLIC OR TRICYCLIC AMINO ACIDS | WARNER LAMBERT CO (US) | 2010-03-10 | — | — | EP | disclosed |
| US-6911555-B2 | Cyclic nitromethyl acetic acid derivatives | PFIZER, INC. (US) | 2005-06-28 | — | — | US | disclosed |
| US-20040116525-A1 | Cyclic nitromethyl acetic acid derivatives | DERRICK ANDREW MICHAEL (GB) | 2004-06-17 | — | — | US | disclosed |
| US-20040092591-A1 | Therapeutic use of fused bicyclic or tricyclic amino acids | BLAKEMORE DAVID CLIVE (GB) | 2004-05-13 | — | — | US | disclosed |
| WO-2004016260-A1 | THERAPEUTIC USE OF FUSED BICYCLIC OR TRICYCLIC AMINO ACIDS | PFIZER LIMITED (GB) | 2004-02-26 | — | — | WO | disclosed |
| US-6596900-B2 | Brain, nervous system, neurodegenerative, gastrointestinal, sleep, rheumatic, and psychological disorders; analgesics, antiepileptic agents | PFIZER INC | 2003-07-22 | — | — | US | disclosed |
| US-20030078300-A1 | Fused bicyclic or tricyclic amino acids | PFIZER INC. | 2003-04-24 | — | — | US | disclosed |