⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634001 | 1.00 | — | — | |
| SCHEMBL13451146 | 1.00 | — | — | |
| SCHEMBL3152983 | 1.00 | — | — | |
| SCHEMBL8344751 | 0.94 | — | — | |
| SCHEMBL3156646 | 0.94 | — | — | |
| SCHEMBL13451210 | 0.94 | — | — | |
| SCHEMBL13450788 | 0.94 | — | — | |
| SCHEMBL9655502 | 0.92 | KMT2A (0.36) | — | |
| SCHEMBL7014493 | 0.92 | KMT2A (0.36) | — | |
| SCHEMBL8344822 | 0.92 | KMT2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379494-B1 | FUSED BICYCLIC OR TRICYCLIC AMINO ACIDS | WARNER LAMBERT CO (US) | 2010-03-10 | — | — | EP | disclosed |
| WO-2004016260-A1 | THERAPEUTIC USE OF FUSED BICYCLIC OR TRICYCLIC AMINO ACIDS | PFIZER LIMITED (GB) | 2004-02-26 | — | — | WO | disclosed |