Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25331476 | 1.00 | APLNR (0.34) | APLNRFFAR3MAPK1TP53NFKB1 | |
| SCHEMBL25331473 | 1.00 | APLNR (0.34) | APLNRFFAR3MAPK1TP53NFKB1 | |
| SCHEMBL15423562 | 1.00 | APLNR (0.34) | APLNRFFAR3MAPK1TP53NFKB1 | |
| SCHEMBL16843480 | 0.77 | CYP3A4 (0.43) | LMNASMN1; SMN2NPSR1 | |
| SCHEMBL21048297 | 0.77 | CYP3A4 (0.43) | LMNASMN1; SMN2NPSR1 | |
| SCHEMBL27045965 | 0.76 | TSHR (0.33) | APLNRFFAR3CYP2C19LMNA | |
| SCHEMBL25332318 | 0.74 | CYP3A4 (0.33) | APLNRFFAR3LMNASMN1; SMN2NPSR1 | |
| SCHEMBL20364187 | 0.74 | TSHR (0.32) | LMNASMN1; SMN2NPSR1 | |
| SCHEMBL19557150 | 0.74 | TSHR (0.32) | LMNASMN1; SMN2NPSR1 | |
| SCHEMBL19557120 | 0.72 | F10 (0.36) | HIF1ALMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025087431-A1 | PAN-KRAS INHIBITOR AND USE THEREOF IN MEDICINES | 贝达药业股份有限公司 | 2025-05-01 | — | — | WO | disclosed |