Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1430821 | 0.81 | RAB9A (0.66) | RAB9AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL30440538 | 0.81 | RAB9A (0.66) | RAB9AMAPTKMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL3302231 | 0.80 | RAB9A (0.64) | RAB9AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL14514903 | 0.79 | RAB9A (0.55) | RAB9AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL838607 | 0.79 | RAB9A (0.68) | RAB9AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL1723416 | 0.79 | RAB9A (0.68) | RAB9AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL3311499 | 0.78 | RAB9A (0.54) | RAB9AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL839206 | 0.78 | RAB9A (0.66) | RAB9AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL12101150 | 0.78 | RAB9A (0.66) | RAB9AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL17450654 | 0.78 | RAB9A (0.66) | RAB9AMAPTKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025099238-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF GASTROINTESTINAL STROMAL TUMOR (GIST) | Universität Duisburg-Essen (DE) | 2025-05-15 | — | — | WO | disclosed |
| EP-4552639-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF GASTROINTESTINAL STROMAL TUMOR (GIST) | Universität Duisburg-Essen (DE) | 2025-05-14 | — | — | EP | disclosed |