SCHEMBL31532999

SCHEMBL31532999

COc1cc(/C=C/C(=O)N2CCN(S(=O)(=O)c3ccc(C#N)cc3)CC2)ccc1O

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.65
ALDH1A1 P00352 1/20 0.65
TRPV1 Q8NER1 3/20 0.60
ROCK2 O75116 2/20 0.57
ACHE P22303 8/20 0.56
GPR183 P32249 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31532991 0.90 KDM4E (0.65) KDM4EALDH1A1TRPV1ROCK2ACHE
SCHEMBL31532989 0.88 ACHE (0.71) KDM4EALDH1A1TRPV1ROCK2ACHE
SCHEMBL31532988 0.87 GPR183 (0.73) KDM4EALDH1A1TRPV1ROCK2ACHE
SCHEMBL31532986 0.87 ACHE (0.71) KDM4EALDH1A1TRPV1ROCK2ACHE
SCHEMBL31533012 0.87 GPR183 (0.73) KDM4EALDH1A1TRPV1ACHEGPR183
SCHEMBL31533002 0.87 KDM4E (0.84) KDM4EALDH1A1TRPV1ROCK2ACHE
SCHEMBL31532990 0.87 KDM4E (0.84) KDM4EALDH1A1TRPV1ROCK2ACHE
SCHEMBL31532997 0.86 KDM4E (0.75) KDM4EALDH1A1TRPV1ROCK2ACHE
SCHEMBL31533014 0.85 GPR183 (0.66) KDM4EALDH1A1TRPV1ROCK2ACHE
SCHEMBL31533003 0.85 KDM4E (0.65) KDM4EALDH1A1TRPV1ROCK2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930543-A Preparation method of novel ferulic acid derivative containing sulfonamide structure and application of ferulic acid derivative in agriculture 贵州工业职业技术学院 2025-05-06 CN disclosed