SCHEMBL315331

SCHEMBL315331

CC1(C)CC(OC(=O)/C=C\C(=O)OC2CC(C)(C)N(Cc3ccccc3)C(C)(C)C2)CC(C)(C)N1Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
KMT2A Q03164 3/20 0.43
GAA P10253 2/20 0.42
HTT P42858 1/20 0.42
AMPD2 Q01433 4/20 0.42
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
BCHE P06276 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
LMNA P02545 1/20 0.37
DRD2 P14416 1/20 0.37
DRD4 P21917 1/20 0.37
DRD3 P35462 1/20 0.37
CYP2D6 P10635 1/20 0.37
HPGD P15428 1/20 0.36
MC4R P32245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL315332 1.00 TSHR (0.43) TSHRKMT2AGAAHTTAMPD2
SCHEMBL1900036 0.96 HCAR2 (0.43) TSHRKMT2AGAAHTTAMPD2
SCHEMBL1900033 0.96 HCAR2 (0.43) TSHRKMT2AGAAHTTAMPD2
SCHEMBL9421827 0.90 TSHR (0.41) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11403013 0.85 TSHR (0.44) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11841173 0.84 TSHR (0.41) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11841166 0.83 TSHR (0.43) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11857985 0.83 TSHR (0.41) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11179317 0.83 CHRM3 (0.43) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11259423 0.82 GAA (0.43) TSHRKMT2AGAAHTTAMPD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3365380-B1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-04-26 EP disclosed
US-11542389-B2 Vinyl chloride polymers and compositions for additive manufacturing AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-01-03 US disclosed
WO-2020058337-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS BOREALIS AG (AT) 2020-03-26 WO disclosed
EP-3626772-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS Borealis AG (AT) 2020-03-25 EP disclosed
US-10365411-B2 Hardcoat film, polarizing plate, liquid crystal display, and method for manufacturing hardcoat film FUJIFILM CORPORATION (JP) 2019-07-30 US disclosed
CN-105849600-B Optical film, polarizing plate and image display device 柯尼卡美能达株式会社 2018-06-22 CN disclosed
US-9951205-B2 Stable compositions of thiabendazole and iodine-containing fungicides LANXESS DEUTSCHLAND GMBH (DE) 2018-04-24 US disclosed
EP-2758462-B1 STABILIZING OF ORGANIC MATERIAL WITH AMINO-TRIAZINE BASED MANNICH-COMPOUNDS BOREALIS AG (AT) 2018-03-07 EP disclosed
US-20170322345-A1 HARDCOAT FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD FOR MANUFACTURING HARDCOAT FILM FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
US-9585384-B2 Stabilization of compounds comprising iodine LANXESS DEUTSCHLAND GMBH (DE) 2017-03-07 US disclosed
US-5194465-A Photostability, graft polymers, unsaturated hindered amine modifier CIBA-GEIGY CORPORATION (US) 1993-03-16 US disclosed
US-5073278-A Oxidation resistant CIBA-GEIGY CORPORATION (US) 1991-12-17 US disclosed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US disclosed
US-5045577-A Coordination catalyst, mixture of stabilizers including a piperidine compound and a phosphite, phosphonite or phosphinite CIBA-GEIGY CORPORATION (US) 1991-09-03 US disclosed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 EP disclosed
US-4929652-A ZINC OR MAGNESIUM CARBOXYLIC SALTS, POLYALKYLPIPERIDINE STABILIZERS CIBA-GEIGY CORPORATION (US) 1990-05-29 US disclosed
US-4894399-A Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY CORPORATION (US) 1990-01-16 US disclosed
US-4880859-A GROUP TRANSFER POLYMERIZATION, COATINGS CIBA-GEIGY CORPORATION (US) 1989-11-14 US disclosed
US-4775386-A Process for photochemical stabilization of undyed and dyed polyamide fibre material and blends thereof with other fibres: copper complex and light stabilizer treatment CIBA-GEIGY CORPORATION (US) 1988-10-04 US disclosed
US-4314933-A 2,2,6,6-TETRAALKYLPIPERIDINE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1982-02-09 US disclosed