Sugi Predict

Sugi Predict / Compounds / SCHEMBL315332

SCHEMBL315332

SCHEMBL315332

CC1(C)CC(OC(=O)C=CC(=O)OC2CC(C)(C)N(Cc3ccccc3)C(C)(C)C2)CC(C)(C)N1Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ GAA P10253 2/20 0.42
▸ HTT P42858 1/20 0.42
▸ AMPD2 Q01433 4/20 0.42
▸ MEN1 O00255 2/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ BCHE P06276 1/20 0.37
▸ HCAR2 Q8TDS4 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ DRD2 P14416 1/20 0.37
▸ DRD4 P21917 1/20 0.37
▸ DRD3 P35462 1/20 0.37
▸ CYP2D6 P10635 1/20 0.37
▸ HPGD P15428 1/20 0.36
▸ MC4R P32245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL315331 1.00 TSHR (0.43) TSHRKMT2AGAAHTTAMPD2
SCHEMBL1900036 0.96 HCAR2 (0.43) TSHRKMT2AGAAHTTAMPD2
SCHEMBL1900033 0.96 HCAR2 (0.43) TSHRKMT2AGAAHTTAMPD2
SCHEMBL9421827 0.90 TSHR (0.41) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11403013 0.85 TSHR (0.44) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11841173 0.84 TSHR (0.41) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11841166 0.83 TSHR (0.43) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11857985 0.83 TSHR (0.41) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11179317 0.83 CHRM3 (0.43) TSHRKMT2AGAAHTTAMPD2
SCHEMBL11259423 0.82 GAA (0.43) TSHRKMT2AGAAHTTAMPD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020058337-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS BOREALIS AG (AT) 2020-03-26 — — WO disclosed
EP-3626772-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS Borealis AG (AT) 2020-03-25 — — EP disclosed
EP-2758462-B1 STABILIZING OF ORGANIC MATERIAL WITH AMINO-TRIAZINE BASED MANNICH-COMPOUNDS BOREALIS AG (AT) 2018-03-07 — — EP disclosed
US-9546261-B2 Stabilizing of organic material with amino-triazine based mannich-compounds BOREALIS AG (AT) 2017-01-17 — — US disclosed
US-9315760-B2 Ashless lubricant composition VANDERBILT CHEMICALS, LLC (US) 2016-04-19 — — US disclosed
US-20150087568-A1 ASHLESS LUBRICANT COMPOSITION VANDERBILT CHEMICALS, LLC 2015-03-26 — — US disclosed
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds BOREALIS AG (AT) 2014-08-21 — — US disclosed
US-20140213493-A1 ASHLESS LUBRICANT COMPOSITION VANDERBILT CHEMICALS, LLC (US) 2014-07-31 — — US disclosed
EP-2758462-A1 STABILIZING OF ORGANIC MATERIAL WITH AMINO-TRIAZINE BASED MANNICH-COMPOUNDS Borealis AG (AT) 2014-07-30 — — EP disclosed
WO-2013041592-A1 STABILIZING OF ORGANIC MATERIAL WITH AMINO-TRIAZINE BASED MANNICH-COMPOUNDS BOREALIS AG (AT) 2013-03-28 — — WO disclosed
US-5268113-A Blend of an oil and a steric hindered amine CIBA-GEIGY CORPORATION (US) 1993-12-07 — — US disclosed
US-5221287-A Blend with polypropylene or polyurethane and hindered amine light stabilizer CIBA-GEIGY CORPORATION (US) 1993-06-22 — — US disclosed
US-5194465-A Photostability, graft polymers, unsaturated hindered amine modifier CIBA-GEIGY CORPORATION (US) 1993-03-16 — — US disclosed
US-5073278-A Oxidation resistant CIBA-GEIGY CORPORATION (US) 1991-12-17 — — US disclosed
US-5057562-A Using steric hindered amine stabilizer CIBA-GEIGY CORPORATION (US) 1991-10-15 — — US disclosed
US-5045577-A Coordination catalyst, mixture of stabilizers including a piperidine compound and a phosphite, phosphonite or phosphinite CIBA-GEIGY CORPORATION (US) 1991-09-03 — — US disclosed
US-4929652-A ZINC OR MAGNESIUM CARBOXYLIC SALTS, POLYALKYLPIPERIDINE STABILIZERS CIBA-GEIGY CORPORATION (US) 1990-05-29 — — US disclosed
US-4894399-A Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY CORPORATION (US) 1990-01-16 — — US disclosed
US-4880859-A GROUP TRANSFER POLYMERIZATION, COATINGS CIBA-GEIGY CORPORATION (US) 1989-11-14 — — US disclosed
US-4775386-A Process for photochemical stabilization of undyed and dyed polyamide fibre material and blends thereof with other fibres: copper complex and light stabilizer treatment CIBA-GEIGY CORPORATION (US) 1988-10-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds PCNA, SOD1, UBE2M TSHR 4491/4885KMT2A 1629/4885GAA 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.