Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548914 | 0.89 | CA12 (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7286654 | 0.87 | — | — | |
| SCHEMBL1720225 | 0.87 | — | — | |
| SCHEMBL1052166 | 0.87 | TSHR (0.42) | KMT2AALDH1A1 | |
| SCHEMBL1440126 | 0.83 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL8225746 | 0.83 | KDM4E (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL22609583 | 0.81 | — | — | |
| SCHEMBL5611395 | 0.81 | — | — | |
| SCHEMBL9872516 | 0.79 | HTR1B (0.34) | MEN1KMT2A | |
| SCHEMBL8068207 | 0.78 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1935912-B1 | Method for manufacturing PIPA-polyols in order to manufacture high-elasticity polyurethane soft foam material | BAYER MATERIALSCIENCE AG (DE) | 2010-03-17 | — | — | EP | disclosed |
| US-20080167394-A1 | Process for the preparation of PIPA polyols for the production of highly elastic flexible polyurethane foams | BAYER MATERIALSCIENCE AG | 2008-07-10 | — | — | US | disclosed |
| EP-1935912-A1 | Method for manufacturing PIPA-polyols in order to manufacture high-elasticity polyurethane soft foam material | Bayer MaterialScience AG (DE) | 2008-06-25 | — | — | EP | disclosed |
| EP-0884338-B1 | Process for production of high resilient polyurethane foam | BAYER AG (DE) | 2002-10-02 | — | — | EP | disclosed |
| US-5977198-A | Process for the production of resilient, flexible polyurethane foams | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| EP-0884338-A1 | Process for production of high resilient polyurethane foam | BAYER AG (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0411400-B1 | Basic condensates | BAYER AG (DE) | 1994-11-30 | — | — | EP | disclosed |
| EP-0411400-A2 | Basic condensates | BAYER AG (DE) | 1991-02-06 | — | — | EP | disclosed |