Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25351229 | 1.00 | HDAC6 (0.50) | HDAC6LRRK2PLK4JAK2MAP4K4 | |
| SCHEMBL25352849 | 0.94 | HDAC6 (0.51) | HDAC6HPGDMEN1RAB9AKMT2A | |
| SCHEMBL30460209 | 0.94 | HDAC6 (0.51) | HDAC6HPGDMEN1RAB9AKMT2A | |
| SCHEMBL25352360 | 0.94 | HDAC6 (0.51) | HDAC6HPGDMEN1RAB9AKMT2A | |
| SCHEMBL25350857 | 0.92 | HDAC6 (0.53) | HDAC6LRRK2HDAC1MGLL | |
| SCHEMBL25351280 | 0.91 | HDAC6 (0.49) | HDAC6LRRK2HDAC1MGLL | |
| SCHEMBL25350447 | 0.91 | HDAC6 (0.49) | HDAC6HDAC1MGLL | |
| SCHEMBL25386481 | 0.88 | HDAC6 (0.46) | HDAC6KDRROCK1HDAC1 | |
| SCHEMBL30425562 | 0.88 | HDAC6 (0.46) | HDAC6KDRROCK1HDAC1 | |
| SCHEMBL25352274 | 0.87 | HDAC6 (0.58) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |