Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25352360 | 1.00 | HDAC6 (0.51) | HDAC6NPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL25352849 | 0.98 | HDAC6 (0.51) | HDAC6NPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL25351229 | 0.94 | HDAC6 (0.50) | HDAC6RAB9AMEN1HPGDKMT2A | |
| SCHEMBL31535153 | 0.94 | HDAC6 (0.50) | HDAC6RAB9AMEN1HPGDKMT2A | |
| SCHEMBL25350857 | 0.93 | HDAC6 (0.53) | HDAC6HDAC1MGLL | |
| SCHEMBL25350447 | 0.91 | HDAC6 (0.49) | HDAC6HDAC1MGLL | |
| SCHEMBL25351280 | 0.91 | HDAC6 (0.49) | HDAC6HDAC1MGLL | |
| SCHEMBL25352274 | 0.88 | HDAC6 (0.58) | HDAC6HDAC1 | |
| SCHEMBL30409208 | 0.88 | HDAC6 (0.58) | HDAC6HDAC1 | |
| SCHEMBL25351893 | 0.84 | HDAC6 (0.51) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |