Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.57 |
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | TEK | Q02763 | 4/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25350687 | 1.00 | HDAC6 (0.57) | HDAC6KDRTEKEPHB4HDAC1 | |
| SCHEMBL31535160 | 0.90 | HDAC6 (0.57) | HDAC6HDAC1ROCK2GSK3BAURKB | |
| SCHEMBL25349454 | 0.90 | HDAC6 (0.57) | HDAC6HDAC1ROCK2GSK3BAURKB | |
| SCHEMBL25349267 | 0.89 | HDAC6 (0.56) | HDAC6HDAC1 | |
| SCHEMBL25351832 | 0.89 | HDAC6 (0.55) | HDAC6KDRTEKEPHB4HDAC1 | |
| SCHEMBL31535162 | 0.89 | HDAC6 (0.55) | HDAC6KDRTEKEPHB4HDAC1 | |
| SCHEMBL24599274 | 0.89 | HDAC6 (0.73) | HDAC6KDRTEKEPHB4 | |
| SCHEMBL25355252 | 0.89 | HDAC6 (0.52) | HDAC6KDRTEKEPHB4HDAC1 | |
| SCHEMBL22557712 | 0.89 | HDAC6 (0.70) | HDAC6KDRTEKEPHB4HDAC1 | |
| SCHEMBL24215833 | 0.89 | HDAC6 (0.56) | HDAC6KDRTEKEPHB4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |