Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25349454 | 1.00 | HDAC6 (0.57) | HDAC6ROCK2PIM1GSK3BAURKB | |
| SCHEMBL29402329 | 0.92 | HDAC6 (0.54) | HDAC6HDAC1 | |
| SCHEMBL22557792 | 0.92 | HDAC6 (0.54) | HDAC6HDAC1 | |
| SCHEMBL25349267 | 0.91 | HDAC6 (0.56) | HDAC6HDAC1 | |
| SCHEMBL25350687 | 0.90 | HDAC6 (0.57) | HDAC6ROCK2GSK3BAURKBHDAC1 | |
| SCHEMBL22557712 | 0.90 | HDAC6 (0.70) | HDAC6HDAC1 | |
| SCHEMBL31535159 | 0.90 | HDAC6 (0.57) | HDAC6ROCK2GSK3BAURKBHDAC1 | |
| SCHEMBL24215833 | 0.90 | HDAC6 (0.56) | HDAC6HDAC1 | |
| SCHEMBL29402321 | 0.90 | HDAC6 (0.70) | HDAC6HDAC1 | |
| SCHEMBL30409985 | 0.90 | HDAC6 (0.56) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |