Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31536674 | 0.85 | SPHK1 (0.41) | SPHK1FAAHBRD4 | |
| SCHEMBL6736498 | 0.80 | SPHK1 (0.38) | SPHK1BRD4GPR119NR1H2 | |
| SCHEMBL6741524 | 0.80 | SPHK1 (0.38) | SPHK1BRD4GPR119NR1H2 | |
| SCHEMBL20263037 | 0.80 | GPR119 (0.40) | SPHK1BRD4GPR119 | |
| SCHEMBL20263034 | 0.80 | GPR119 (0.40) | SPHK1BRD4GPR119 | |
| SCHEMBL16553345 | 0.76 | SPHK1 (0.46) | SPHK1BRD4GPR119NR1H2HSD11B2 | |
| SCHEMBL16553346 | 0.76 | SPHK1 (0.46) | SPHK1BRD4GPR119NR1H2HSD11B2 | |
| SCHEMBL15336587 | 0.76 | SPHK1 (0.46) | SPHK1BRD4GPR119NR1H2HSD11B2 | |
| SCHEMBL30669036 | 0.76 | SPHK1 (0.46) | SPHK1BRD4GPR119NR1H2HSD11B2 | |
| SCHEMBL6208986 | 0.75 | SPHK1 (0.39) | SPHK1BRD4HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025080946-A2 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-04-17 | — | — | WO | disclosed |